منابع مشابه
Recent research highlights importance of trials halted 10 years ago.
NSABP's B-14 trial was originally launched to evaluate whether women with lymph node – negative, estrogen receptor – positive breast cancer benefi t from tamoxifen treatment. Researchers also designed the trial to test the duration of tamoxifen therapy necessary to get the most benefi t from the drug. In late 1995, an analysis of the study data revealed that the benefi ts of 5 years of tamoxife...
متن کاملEvaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملEvidence Based Medicine: Clinical Trials
Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...
متن کاملevidence based medicine: clinical trials
evidence based medicine is very important for success of modern medicine. it is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. it not only identifi...
متن کاملCharacteristics of Clinical Trials in Iran: A Sample of 5000 Trials Registered in IRCT
Background and Objectives: A considerable number of clinical trials are conducted in Iran each year. Not much is known about the characteristics of them, this study aimed to investigate key characteristics of Iranian clinical trials. Methods: All clinical trial protocols registered in IRCT until November 2013 were selected. Text mining techniques were used to extract information from data t...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2000
ISSN: 1087-0156,1546-1696
DOI: 10.1038/81033